level for all papers published in related disciplines. Figure 1: Stem Cell types and characteristics, publication output, growth and field-weighted citation impact. The results show that more than half of all stem cell publications do not use keywords related to either theme (see Figure 4). The first and most controversial source is an embryonic cell that comes from a three to five day old blastocyst. I believe the biggest impact to date of iPS cell technology is not regenerative medicine, but in making disease models, drug discovery, and toxicology testing Shinya Yamanaka, Director Center for iPS Cell Research and Application (CiRA Kyoto University. For more detailed information on stem cells, please refer to our study (3). Reflecting the fields ongoing development and clinical promise, approximately half of all stem cell publications are associated with regenerative medicine or drug development, a trend that is particularly pronounced in iPS cell research. To date, 58 siblings have been created for this purpose. Scientists working in tissue engineering and regenerative medicine hope to someday use the cells from the intended recipient to create a new custom designed cell type or even a perfectly matched organ to replace damaged tissue. Umbilical cells would be even more acceptable if genetic matches could be determined before an ovum is fertilized and an embryo is formed. This property opens the door to clinical applications such as cell and organ replacement (2) and may accelerate drug discovery, drug screening and toxicological assessment.
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This could lead to an increased risk of cancer in already compromised patients. The origin of the first argument is the source and process for producing some stem cells, specifically embryonic stem cells. IPS cell papers show explosive growth and the highest impact of all types of stem cell research papers. The third and most recently discovered source is adult stem cells, or induced pluripotent stem cells (iPS). A blastocyst is a ball of undifferentiated cells that forms after an ovum is fertilized. The second very rich source of stem cells is the umbilical cord. San Diego: Elsevier, 2013,.
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